Data engineering & big data
Inventory, clean, integrate, and harmonize complex datasets across participants, sessions, and cohorts.
You receive: Analysis-ready datasets, quality reports, and documented processing workflows.
DATA SCIENCE · AI · SCIENTIFIC COMPUTING
Complex data.
Useful answers.
Imperium Systems combines scientific consulting with proprietary AI product development. We build reliable analytical workflows, research software, and human-centered systems that turn complex information into usable knowledge.
Matthew P. Gunn, Ph.D.Computational neuroscientist · 15+ years of research experience
Illinois BEP CertifiedMinority Business EnterpriseActive SAM.gov RegistrationRegistered for All AwardsIllinois Procurement GatewayActive / Accepted
01 / PRODUCTS & VENTURES
Research depth.
Product ambition.
Alongside its scientific services, Imperium develops proprietary AI products shaped by responsible design and real human needs.
APPLIED INTELLIGENCE INITIATIVE · MVP IN DEVELOPMENT
Project LM-01
Personal Intelligence Platform — Working Title
Imperium Systems is developing a privacy-conscious AI platform that helps people organize complex information, reflect on goals, and make better-informed decisions.
Explore Project LM-0102 / SERVICES
Expertise for the question.
Tools for the work.
Engage Imperium for a defined analysis, a data-processing workflow, or a custom software project. Scope and deliverables are agreed for each engagement.
Statistical analysis & AI
Evaluate associations, changes over time, and predictive models using statistics and machine learning.
You receive: Reproducible code, model evaluation, figures, and interpretation notes.
Scientific software & automation
Build custom tools and AI-assisted workflows in Python, MATLAB, and R to make repeated work easier to run and maintain.
You receive: Reusable software, configuration guidance, and handoff documentation.
Specialist research capabilities
EEG / ERP
Resting-state and task-based EEG, event-related potentials, spectral analysis, current source density (CSD), and functional connectivity.
Functional MRI
Resting-state and task-based fMRI, task contrasts, functional connectivity, brain networks, and individual differences.
Biobehavioral research
Behavioral tasks, reaction times, questionnaires, longitudinal outcomes, and integrated biological and behavioral data from drug-administration studies.
Genetics & biomarkers
Genome-wide association studies (GWAS), genetic and phenotypic data integration, endophenotypes, and candidate biomarker research.
03 / SELECTED WORK
Methods you can inspect.
Research you can read.
Selected examples from Matthew’s scientific software and academic research.
PYTHON / NEUROIMAGING
NeuroToolbox
Neuroimaging tools for normative modeling, multivariate analysis, network metrics, and configurable workflows.
Explore the repositoryMATLAB / EEG
Spatiotemporal PCA
A MATLAB and EEGLAB workflow for ERP decomposition, parallel analysis, rotation, and reproducible logging.
Explore the repositorySelected peer-reviewed publications
2024Smoking Progression and Nicotine-Enhanced Reward Sensitivity Predicted by Resting-State Functional Connectivity in Salience and Executive Control Networks
Gunn et al. · Nicotine & Tobacco Research
Depression, anxiety, and genetics shape smoking risk through salience networks
Gunn et al. · Psychiatry Research: Neuroimaging
Tuning the brain: Intrinsic resting-state connectomes distinguish major depressive disorder from social anxiety disorder in salience and limbic circuits
Gunn et al. · Journal of Affective Disorders
04 / MEET THE FOUNDER
Scientific depth.
Practical execution.
Matthew P. Gunn is a computational neuroscientist and scientific software developer with more than 15 years of research experience. He earned his Ph.D. at Southern Illinois University Carbondale in 2024, following degrees in psychology and chemistry/biochemistry.
His academic research experience spans Southern Illinois University Carbondale, the University of Illinois Chicago, McLean Hospital, and Harvard Medical School. His work examines brain connectivity, nicotine and cannabis responses, depression, and anxiety.
Awards & entrepreneurship
NIH / NIDA F32 Fellowship
Awarded 2026 through McLean Hospital · 1F32DA067053-01
Co-founder & Stage II Winner
2025 NIDA “Start an SUD Startup” Challenge · Team award announced August 31, 2026.
NSF I-Corps — University of Michigan Node
Completed customer-discovery and commercialization training, 2025.
Affiliations and recognition reflect Matthew’s academic and team experience. Imperium Systems LLC is an independent business.
Books & practical guides from the team
Three Ways to Use AI as a Thought Partner
A Practical Guide to Challenging Ideas, Auditing Logic, and Widening Perspective
View on Amazon (opens in a new tab)The GPT Engineering Loop
A Field Guide to Reliable AI Coding Workflows · Mini-book
View on Amazon (opens in a new tab)05 / BUSINESS CREDENTIALS
Clear credentials.
Straightforward procurement.
Certifications, registrations, and startup program membership for Imperium Systems LLC.
STATE CERTIFICATION
Illinois BEP Certified
Minority Business Enterprise · Illinois Commission on Equity and Inclusion
- Annual renewal
- August 10, 2027
FEDERAL REGISTRATION
SAM.gov — Active
Registered for All Awards
- Registration expiration
- August 6, 2027
STARTUP PROGRAM
NVIDIA Inception Member
Imperium Systems LLC is a member of NVIDIA Inception, a program supporting startups building with AI and accelerated computing.
Explore NVIDIA Inception (opens in a new tab)Additional registration details & renewal dates
Illinois BEP
Certified August 10, 2026. Certification expiration: August 10, 2033. Continued certification requires the annual No Change Affidavit; next renewal August 10, 2027.
SAM.gov
Activated August 20, 2026. The record also lists a self-certified Small Disadvantaged Business designation.
Illinois Procurement Gateway
Active (Accepted) prime-supplier registration · Expires July 31, 2027.
Illinois Small Business Set-Aside Program
Registered in SBSP, as recorded in the accepted Illinois Procurement Gateway profile.
Illinois State Board of Elections
Business registered · Record last updated July 22, 2026.
Data security
Our security program aims to meet the NBDC Data Hub’s security requirements. Project planning addresses data access, the computing environment, secure transfers, and retention requirements.
06 / LET’S TALK
What do you need
to move forward?
Tell us whether you are exploring a product collaboration, a research question, or a defined analytical project. We’ll identify the right next conversation.
Contact Matthew directly
Choose Gmail or your email app to start a conversation about your project.